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Body Filler | South Korea HYALMASS Booster Skin Regeneration Booster | HA PDRN Exosome | Tri-Phase System 50 mg/mlHA Concentration20 ugPDRN15 %ExosomeTri phaseDelivery Overview HYALMASS is a skin-regeneration booster built on a Tri-Phase Delivery System that combines three actives – 50 mg/ml hyaluronic acid as 1.5 MDa microspheres for deep hydration, salmon-DNA PDRN for tissue repair, and a 15% BM-MSC exosome concentrate to support collagen synthesis. It targets hydration, repair, and regeneration together, applied through microneedling or mesotherapy. Composition Primary ActiveHyaluronic Acid50 mg/ml | 1.5 MDaHigh-concentration hyaluronic acid delivered as 1.5 MDa microspheres, forming a dermal depot for sustained deep hydration.RegenerativePDRN20 ug | salmon DNASalmon-DNA-derived polydeoxyribonucleotide (PDRN) is included to support tissue repair and skin regeneration.RegenerativeExosome Concentrate15% | BM-MSC 80-120nmBM-MSC-derived exosomes in the 80-120 nm range are included to help stimulate collagen synthesis and cell signalling. Approved Indications 01Deep skin hydration and moisture replenishment02Skin regeneration and tissue repair support03Collagen synthesis stimulation04Improvement of skin elasticity05Overall skin-quality and radiance enhancement06Facial and body skin rejuvenation Why HYALMASS 01Tri-Phase Delivery SystemCombines three actives in one system – HA microspheres, PDRN, and exosomes – targeting hydration, repair, and regeneration together.02High HA Concentration50 mg/ml hyaluronic acid as 1.5 MDa microspheres provides a dermal depot intended for sustained deep hydration.03PDRN Exosome SynergySalmon-DNA PDRN pairs with BM-MSC exosomes to support tissue repair and collagen-stimulating signalling.04Multi-Target Skin RenewalAddresses hydration, cellular repair, and regeneration in a single treatment rather than a single-action booster. Triple-active systemHYALMASS converges three regenerative classes in one Tri-Phase system – hyaluronic acid for hydration, PDRN for tissue repair, and exosomes for collagen-stimulating signalling – aimed at multi-target skin renewal rather than hydration alone. Standard Dosing Guide Reference only – adjust per patient anatomy and clinical judgement Microneedling (face)Depth0.5-1.0 mm depthInstrument~2 ml per sessionMicroneedling (body)Depth1.5 mm depthInstrumentAs appropriateMesotherapyDepthFacial injection gridInstrument~0.05 ml per pointScheduleDepthBi-weekly intervalInstrumentPer treatment cycle Specifications HA Concentration50 mg/ml (1.5 MDa microspheres)PDRN20 ug (salmon DNA derived)Exosome15% concentrate (BM-MSC, 80-120 nm)Delivery SystemTri-PhaseApplicationMicroneedling / mesotherapyUseSingle-patient, professional use only FAQ What are the three active components in HYALMASS? HYALMASS is built around a Tri-Phase Delivery System combining three actives: hyaluronic acid at 50 mg/ml (as 1.5 MDa microspheres) for deep hydration, PDRN (polydeoxyribonucleotide) derived from salmon DNA for tissue repair, and a 15% exosome concentrate (BM-MSC-derived, 80-120 nm) to support collagen synthesis. The combination targets hydration, repair, and regeneration together.What does PDRN do in this formula? PDRN (polydeoxyribonucleotide) is a DNA-derived component, here sourced from salmon DNA, included for its role in supporting tissue repair and skin regeneration. In HYALMASS it works alongside the hyaluronic acid and exosome components rather than on its own.What is the role of the exosome concentrate? The 15% exosome concentrate uses BM-MSC-derived exosomes in the 80-120 nm range. Exosomes are nano-scale vesicles that carry signalling cargo between cells; in this product they are included to help stimulate collagen synthesis and support skin regeneration.How is HYALMASS applied? It is described for use via microneedling – around 0.5-1.0 mm depth on the face and 1.5 mm on body areas, roughly 2 ml per session – and via mesotherapy using a facial injection grid with small volumes (about 0.05 ml) per point on a bi-weekly cycle. The treating practitioner sets the exact protocol.How does HYALMASS differ from a single-ingredient HA booster? A standard skin booster typically relies on hyaluronic acid alone for hydration. HYALMASS adds two further regenerative classes – PDRN and exosomes – so that beyond hydration it also targets tissue repair and collagen-stimulating signalling in the same treatment. It contains marine-derived (salmon) material, so it is not suitable for patients with relevant allergies. Related Products Skin BoosterHyalmass Aqua ExosomeHA PDRN ExosomeView ->Body FillerDeneB 10ml20 mg/ml lidocaineView ->Body FillerCelosome X-Shape24 mg/ml | 10 mlView -> Safety For Licensed Healthcare Professionals Only HYALMASS is intended for administration by licensed healthcare professionals only. It contains marine-derived (salmon) ingredients and is contraindicated for patients with seafood or related allergies, as well as in pregnancy or lactation and in those with known hypersensitivity to any component. Aseptic technique is essential. Individual results may vary with skin condition and application technique. Regulatory Notice: HYALMASS regulatory status varies by jurisdiction. Buyers are responsible for verifying applicable local regulations prior to import and use. FillersFairy is a distributor and not liable for clinical outcomes. Informational content only – not medical advice.








